Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Very Short Mitochondrial DNA Fragments and Heteroplasmy in Human Plasma.

Scientific reports - 4 Nov 2016

Zhang Ruoyu, Nakahira Kiichi, Guo Xiaoxian, Choi Augustine M K, Gu Zhenglong

Abstract excerpt

Cell free DNA (cfDNA) has received increasing attention and has been studied in a broad range of clinical conditions. However, few studies have focused on mitochondrial DNA (mtDNA) in the cell free form. We optimized DNA isolation and sequencing library preparation protocols to better retain short DNA fragments from plasma, and applied these optimized methods to plasma samples from patients with sepsis. Our...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bone Marrow Transplantation
Share to Cell-Free Nucleic Acids
Share to DNA, Mitochondrial

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to High-Throughput Nucleotide Sequencing

Share to Leukocytes

Share to Molecular Weight

Share to Plasma

Share to Transplantation Chimera

Source

Open in PubMed Open full text

Identifiers

PMID: 27811968
DOI: 10.1038/srep36097
PMCID: PMC5095883

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Very Short Mitochondrial DNA Fragments and Heteroplasmy in Human Plasma.PMID 27811968Read ↗

Single-stranded DNA library preparation uncovers the origin and diversity of ultrashort cell-free DNA in plasmaSemantic proximity Read ↗

Direct capture and sequencing reveal ultra-short single-stranded DNA in biofluidsSemantic proximity Read ↗

Plasma contains ultrashort single-stranded DNA in addition to nucleosomal cell-free DNASemantic proximity Read ↗

Single-stranded DNA library preparation uncovers the origin and diversity of ultrashort cell-free DNA in plasma.Semantic proximity Read ↗

NGS-based accurate and efficient detection of circulating cell-free mitochondrial DNA in cancer patientsSemantic proximity Read ↗

Short single-stranded DNAs with putative non-canonical structures comprise a new class of plasma cell-free DNASemantic proximity Read ↗

Comparison of the structures and topologies of plasma extracted circulating nuclear and mitochondrial cell-free DNASemantic proximity Read ↗

The circulating cell-free DNA landscape in sepsis is dominated by impaired liver clearanceSemantic proximity Read ↗

An automated, high-throughput methodology optimized for quantitative cell-free mitochondrial and nuclear DNA isolation from plasmaSemantic proximity Read ↗

Automated size selection for short cell-free DNA fragments enriches for circulating tumor DNA and improves error correction during next generation sequencing.Semantic proximity Read ↗

Novel method for multiplexed full-length single-molecule sequencing of the human mitochondrial genomeSemantic proximity Read ↗

Application of cell-free DNA sequencing in characterization of bloodborne microbes and the study of microbe-disease interactionsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.