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Article

Origin of Plasma Cell-free DNA after Solid Organ Transplantation

1 Mar 2003

Abstract excerpt

Despite current interest in the biology and diagnostic application of plasma cell-free DNA (1), there is little knowledge regarding the cellular origin of this DNA. Recently, we have used a sex-mismatched bone marrow transplantation model to study the relative contributions of hematopoietic and nonhematopoietic cells to circulating DNA (2). We have demonstrated that the predominant proportion of plasma DNA...

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PMID: 12600963
DOI: 10.1373/49.3.495

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