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Transrenal DNA testing: progress and perspectives

1 Mar 2006

Abstract excerpt

Transrenal DNA (Tr-DNA) is a recently discovered class of extracellular urinary DNA that originates from cells dying throughout the body. Postapoptotic DNA is known to appear in the circulating plasma, but it is now recognized that a portion of these fragments cross the kidney barrier and appear in urine in the form of 150-200-bp fragments. Tr-DNA containing fetal sequences has been isolated from the urine of...

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PMID: 16512776
DOI: 10.1586/14737159.6.2.153

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