Article
Plasma nucleic acid analysis by massively parallel sequencing: pathological insights and diagnostic implications
4 Jul 2011
Abstract excerpt
Over the past 15 years there has been increasing interest in the biology and diagnostic applications of circulating DNA in the plasma of human subjects. In particular, DNA from a fetus, a tumour, a transplanted organ and injured tissues has been found in the plasma of pregnant women, cancer patients, transplant recipients and patients suffering from multiple pathologies, respectively. The advent of massively...
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