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Article

Molecular analysis of the yeast VPS3 gene and the role of its product in vacuolar protein sorting and vacuolar segregation during the cell cycle.

The Journal of cell biology - 1 Sept 1990

Raymond C K, O'Hara P J, Eichinger G, Rothman J H, Stevens T H

Abstract excerpt

vps3 mutants of the yeast Saccharomyces cerevisiae are impaired in the sorting of newly synthesized soluble vacuolar proteins and in the acidification of the vacuole (Rothman, J. H., and T. H. Stevens. Cell. 47:1041-1051; Rothman, J. H., C. T. Yamashiro, C. K. Raymond, P. M. Kane, and T. H. Stevens. 1989. J. Cell Biol. 109:93-100). The VPS3 gene, which was cloned using a novel selection procedure, encodes a low...

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PMID: 2202738
DOI: 10.1083/jcb.111.3.877
PMCID: PMC2116300

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