Article
A yeast protein related to a mammalian Ras-binding protein, Vps9p, is required for localization of vacuolar proteins.
Molecular and cellular biology - 1 May 1996
Burd C G, Mustol P A, Schu P V, Emr S D
Abstract excerpt
In the yeast Saccharomyces cerevisiae, mutations in vacuolar protein sorting (VPS) genes result in secretion of proteins normally localized to the vacuole. Characterization of the VPS pathway has provided considerable insight into mechanisms of protein sorting and vesicle-mediated intracellular transport. We have cloned VPS9 by complementation of the vacuolar protein sorting defect of vps9 cells, characterized...
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