Article
Roles of the VMA3 gene product, subunit c of the vacuolar membrane H(+)-ATPase on vacuolar acidification and protein transport. A study with VMA3-disrupted mutants of Saccharomyces cerevisiae.
The Journal of biological chemistry - 25 Oct 1990
Umemoto N, Yoshihisa T, Hirata R, Anraku Y
Abstract excerpt
VMA3, a structure gene of the vacuolar membrane H(+)-ATPase subunit c of Saccharomyces cerevisiae, has been cloned and characterized. The VMA3 gene encodes a hydrophobic polypeptide with 160 amino acids as reported previously by Nelson and Nelson (Nelson, H., and Nelson, N. (1989) FEBS Lett. 247,...
Topics
- Anti-Bacterial Agents
- Biological Transport
- Blotting, Western
- Cell Compartmentation
- Cloning, Molecular
- Endocytosis
- Fungal Proteins
- Genes, Fungal
- Hydrogen-Ion Concentration
- Macrolides
- Macromolecular Substances
- Membrane Proteins
- Mutation
- Protein Precursors
- Proton-Translocating ATPases
- Restriction Mapping
- Saccharomyces cerevisiae
- Vacuoles