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Article

Isolation and characterization of PEP3, a gene required for vacuolar biogenesis in Saccharomyces cerevisiae.

Molecular and cellular biology - 1 Dec 1991

Preston R A, Manolson M F, Becherer K, Weidenhammer E, Kirkpatrick D, Wright R, Jones E W

Abstract excerpt

The Saccharomyces cerevisiae PEP3 gene was cloned from a wild-type genomic library by complementation of the carboxypeptidase Y deficiency in a pep3-12 strain. Subclone complementation results localized the PEP3 gene to a 3.8-kb DNA fragment. The DNA sequence of the fragment was determined; a 2,754-bp open reading frame predicts that the PEP3 gene product is a hydrophilic, 107-kDa protein that has no significant...

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Source

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Identifiers

PMID: 1944264
DOI: 10.1128/mcb.11.12.5801-5812.1991
PMCID: PMC361722

Genes

VPS18

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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