Article
Characterization of yeast Vps33p, a protein required for vacuolar protein sorting and vacuole biogenesis.
Molecular and cellular biology - 1 Sept 1990
Banta L M, Vida T A, Herman P K, Emr S D
Abstract excerpt
vps33 mutants missort and secrete multiple vacuolar hydrolases and exhibit extreme defects in vacuolar morphology. Toward a molecular understanding of the role of the VPS33 gene in vacuole biogenesis, we have cloned this gene from a yeast genomic library by complementation of a temperature-sensit...
Topics
- Alleles
- Amino Acid Sequence
- Base Sequence
- Carrier Proteins
- Cloning, Molecular
- Escherichia coli
- Fungal Proteins
- Gene Library
- Molecular Sequence Data
- Mutation
- Phenotype
- Restriction Mapping
- Saccharomyces cerevisiae
- Saccharomyces cerevisiae Proteins
- Sequence Homology, Nucleic Acid
- Vacuoles
- Vesicular Transport Proteins