Article
Characterization of yeast Vps33p, a protein required for vacuolar protein sorting and vacuole biogenesis.
Molecular and cellular biology - 1 Sept 1990
Banta L M, Vida T A, Herman P K, Emr S D
Abstract excerpt
vps33 mutants missort and secrete multiple vacuolar hydrolases and exhibit extreme defects in vacuolar morphology. Toward a molecular understanding of the role of the VPS33 gene in vacuole biogenesis, we have cloned this gene from a yeast genomic library by complementation of a temperature-sensitive vps33 mutation. Gene disruption demonstrated that VPS33 was not essential but was required for growth at high...
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