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Article

Rapid identification of CYP2C8 polymorphisms by high resolution melting analysis.

Clinica chimica acta; international journal of clinical chemistry - 18 Jan 2012

Chang Chun-Chi, Lin Pei-Chin, Lin Ching-Hsiung, Yeh Kun-Tu, Hung Hsiao-Yu, Chang Jan-Gowth

Abstract excerpt

BACKGROUND: Cytochrome P450 (CYP) 2C8 is the principal enzyme responsible for the metabolism of arachidonic acid and various drugs, and influences drug-drug interactions and some associated diseases. Large interindividual differences in CYP2C8 enzymatic activity and several nonsynonymous genetic variations have been reported in different races. Therefore, how to identify CYP2C8 polymorphisms efficiently for...

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PMID: 22027337
DOI: 10.1016/j.cca.2011.10.005

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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