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Article

Developing and Evaluating the HRM Technique for Identifying Cytochrome P450 2D6 Polymorphisms.

Journal of clinical laboratory analysis - 1 May 2015

Lu Hsiu-Chin, Chang Ya-Sian, Chang Chun-Chi, Lin Ching-Hsiung, Chang Jan-Gowth

Abstract excerpt

BACKGROUND: Cytochrome P450 2D6 is one of the important enzymes involved in the metabolism of many widely used drugs. Genetic polymorphisms of CYP2D6 can affect its activity. Therefore, an efficient method for identifying CYP2D6 polymorphisms is clinically important. METHODS: We developed a high-resolution melting (HRM) analysis to investigate CYP2D6 polymorphisms. Genomic DNA was extracted from peripheral blood...

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Identifiers

PMID: 24798984
DOI: 10.1002/jcla.21754
PMCID: PMC6806731

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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