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Article

[Duplex genotyping of CYP2C192 and CYP2C193 by high-resolution melting curve analysis].

Yi chuan = Hereditas - 1 Jul 2013

Cao Chun-Ge, Sun Hai-Yan, Zhou Fang-Fang, Wang Shi-Ming, Chen Hong-Yan, Lu Da-Ru

Abstract excerpt

Clopidogrel is a widely used anti-platelet agent for the prevention of arterial thrombosis. It has been suggested that clopidogrel may be less effective in inhibiting platelet aggregation among patients who are carriers of CYP2C19*2 and CYP2C19*3, two loss-of-function CYP2C19 alleles, which are associated with reduced conversion of clopidogrel to its active metabolite. The objective of this research was to...

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PMID: 23853364
DOI: 10.3724/sp.j.1005.2013.00923

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