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Article

Rapid screening for targeted genetic variants via high-resolution melting curve analysis.

Clinical chemistry and laboratory medicine - 1 Mar 2017

Chambliss Allison B, Resnick Molly, Petrides Athena K, Clarke William A, Marzinke Mark A

Abstract excerpt

BACKGROUND: Current methods for the detection of single nucleotide polymorphisms (SNPs) associated with aberrant drug-metabolizing enzyme function are hindered by long turnaround times and specialized techniques and instrumentation. In this study, we describe the development and validation of a high-resolution melting (HRM) curve assay for the rapid screening of variant genotypes for targeted genetic...

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Identifiers

PMID: 27732553
DOI: 10.1515/cclm-2016-0603
PMCID: PMC5550898

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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