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Article

High resolution melting method to detect single nucleotide polymorphism of VKORC1 and CYP2C9.

International journal of clinical and experimental pathology - 1 Jan 2014

Chen Chunxia, Li Siyue, Lu Xiaojun, Tan Bin, Huang Chunyan, Qin Li

Abstract excerpt

Single nucleotide polymorphisms (SNPs) of VKORC (1173T/C, rs9934438) and CYP2C9 (1075A/C, rs1057910) are major contributory factors on the sensitivity of warfarin in Chinese. Analysis of the two genomic loci could help warfarin treatment individual from bleeding or thrombosis events. An assay with the advantages of simplicity, speed, high sensitivity and low cost for genotyping is calling for clinical...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 24966969
PMCID: PMC4069951

Genes

VKORC1

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