Article
[Development of the high resolution melting method for genotyping CYP2C9*3 (1075A/C, rs1057910) and VKORC1 (-1639A/G, rs9923231)].
Zhonghua xin xue guan bing za zhi - 1 Jun 2012
Cui Guang-lin, Ding Hu, Xu Yu-jun, Chen Chen, Wang Dao-wen
Abstract excerpt
OBJECTIVE: To establish the high-resolution melting curve (HRM) approach for genotyping CYP2C9*3 (1075A/C, rs1057910) and VKORC1 (-1639A/G, rs9923231) and explore its value on estimation of the Warfarin initial dose in comparison with various traditional genotyping methods. METHODS: CYP2C9*3 (1075A/C, rs1057910) and VKORC1 (-1639A/G, rs9923231) genotyping was detected in 100 patients receiving Warfarin therapy by...
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