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Somatic mutations in the D-loop of mitochondrial DNA in oral squamous cell carcinoma.

European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery - 1 Jun 2012

Liu Shih-An, Jiang Rong-San, Chen Fun-Jou, Wang Wen-Yi, Lin Jin-Ching

Abstract excerpt

We aimed to characterize somatic mutations in the D-loop of mitochondrial DNA (mtDNA) and their impact on survival in oral squamous cell carcinoma patients in an endemic betel quid chewing area. Histologically confirmed oral cancer and corresponding non-tumor tissues were obtained from 59 patients. The D-loop of mtDNA sequence in a patient's non-cancerous tissues was compared with that of paired oral cancer...

Topics

Carcinoma, Squamous Cell
DNA, Mitochondrial
Female
Follow-Up Studies
Humans
Male
Middle Aged
Mitochondria
Mouth Neoplasms
Mutation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Retrospective Studies

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Identifiers

PMID: 22020698
DOI: 10.1007/s00405-011-1806-5

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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