Article
Impact of somatic mutations in the D-loop of mitochondrial DNA on the survival of oral squamous cell carcinoma patients.
PloS one - 1 Jan 2015
Lin Jin-Ching, Wang Chen-Chi, Jiang Rong-San, Wang Wen-Yi, Liu Shih-An
Abstract excerpt
OBJECTIVES: The aim of this study was to investigate somatic mutations in the D-loop of mitochondrial DNA (mtDNA) and their impact on survival in oral squamous cell carcinoma patients. MATERIALS AND METHODS: Surgical specimen confirmed by pathological examination and corresponding non-cancerous tissues were collected from 120 oral squamous cell carcinoma patients. The sequence in the D-loop of mtDNA from...
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