Article
Delta-like 1-Lysine613 regulates notch signaling.
Biochimica et biophysica acta - 1 Dec 2011
Zhang Liguo, Widau Ryan C, Herring B Paul, Gallagher Patricia J
Abstract excerpt
Delta ligands are important for regulating Notch signaling through transcellular stimulation of Notch receptors. The cytoplasmic tails of Delta ligands have multiple potential regulatory sites including several lysine residues that are putative targets for ubiquitination by the E3 ubiquitin ligases, Mind Bomb and Neuralized. To identify possible roles for specific lysine residues in the cytoplasmic tail of the...
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