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Article

Structure-function analysis of delta trafficking, receptor binding and signaling in Drosophila.

Genetics - 1 Dec 2006

Parks Annette L, Stout Jane R, Shepard Scott B, Klueg Kristin M, Dos Santos Ana A, Parody Todd R, Vaskova Martina, Muskavitch Marc A T

Abstract excerpt

The transmembrane proteins Delta and Notch act as ligand and receptor in a conserved signaling pathway required for a variety of cell fate specification events in many organisms. Binding of Delta to Notch results in a proteolytic cascade that releases the Notch intracellular domain, allowing it t...

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Share to Caenorhabditis elegans Proteins
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 17028337
DOI: 10.1534/genetics.106.061630
PMCID: PMC1698634

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17028337-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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