Article
Critical roles of chemokine receptor CCR10 in regulating memory IgA responses in intestines.
Proceedings of the National Academy of Sciences of the United States of America - 8 Nov 2011
Hu Shaomin, Yang KangKang, Yang Jie, Li Ming, Xiong Na
Abstract excerpt
Chemokine receptor CCR10 is expressed by all intestinal IgA-producing plasma cells and is suggested to play an important role in positioning these cells in the lamina propria for proper IgA production to maintain intestinal homeostasis and protect against infection. However, interfering with CCR10 or its ligand did not impair intestinal IgA production under homeostatic conditions or during infection, and the in...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
