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Article

CXCR3/CXCL10 Axis Shapes Tissue Distribution of Memory Phenotype CD8+ T Cells in Nonimmunized Mice.

Journal of immunology (Baltimore, Md. : 1950) - 1 Jan 2018

Alanio Cécile, Barreira da Silva Rosa, Michonneau David, Bousso Philippe, Ingersoll Molly A, Albert Matthew L

Abstract excerpt

The preimmune repertoire consists of mature T lymphocytes that have not yet been stimulated in the periphery. Memory phenotype (MP) cells have been reported as part of the preimmune repertoire (i.e., T cells bearing memory markers despite lack of engagement with cognate Ag); however, little is known about their trafficking and function. In this study, we hypothesized that MP cells, naive to TCR stimulation,...

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Topics

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Share to CD8-Positive T-Lymphocytes
Share to Cells, Cultured

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Chemokine CXCL10

Share to Immunologic Memory

Share to Mice, Inbred C57BL

Share to Mice, Knockout

Share to Receptors, Antigen, T-Cell

Share to Receptors, CXCR3

Source

Identifiers

PMID: 29187588
DOI: 10.4049/jimmunol.1700564

Genes

CXCL10
CXCR3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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