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Article

Osteoblast extracellular Ca2+ -sensing receptor regulates bone development, mineralization, and turnover.

Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research - 1 Dec 2011

Dvorak-Ewell Melita M, Chen Tsui-Hua, Liang Nathan, Garvey Caitlin, Liu Betty, Tu Chialing, Chang Wenhan, Bikle Daniel D, Shoback Dolores M

Abstract excerpt

The extracellular Ca(2+) -sensing receptor (CaR), a G protein-coupled receptor responsible for maintenance of calcium homeostasis, is implicated in regulation of skeletal metabolism. To discern the role of the osteoblast CaR in regulation of bone development and remodeling, we generated mice in which the CaR is excised in a broad population of osteoblasts expressing the 3.6-kb a(1) (I) collagen promoter....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 21956637
DOI: 10.1002/jbmr.520
PMCID: PMC3222747

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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