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Article

Functional characterization of osteoblasts and osteoclasts from alkaline phosphatase knockout mice.

Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research - 1 Oct 2000

Wennberg C, Hessle L, Lundberg P, Mauro S, Narisawa S, Lerner U H, Millán J L

Abstract excerpt

Tissue nonspecific alkaline phosphatase (TNAP) knockout (ko) mice manifest defects in bone mineralization that mimic the phenotypic abnormalities of infantile hypophosphatasia. In this article, we have searched for phenotypic differences between calvarial osteoblasts and osteoclasts in wild-type (wt), heterozygous and homozygous TNAP null mice. In vitro release of 45Ca from calvarial bones, with and without...

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Source

Identifiers

PMID: 11028439
DOI: 10.1359/jbmr.2000.15.10.1879

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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