Article
Apolipoprotein E-e4, processing speed, and white matter volume in a genetically enriched sample of midlife adults.
American journal of Alzheimer's disease and other dementias - 1 Sept 2011
Ready Rebecca E, Baran B, Chaudhry M, Schatz K, Gordon J, Spencer R M C
Abstract excerpt
Healthy midlife children of a parent with Alzheimer's disease ([AD] N = 23; 9 male) participated in neuropsychological testing, and magnetic resonance imaging (MRI) of brain volumetrics were obtained. In all, 35% of the sample were apolipoprotein E (ApoE)-e4 positive (n = 8; 5 male). The ApoE-e4 group exhibited significantly slower performances on an executive function and processing speed measure and had less...
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