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Article

Impact of APOE on the healthy aging brain: a voxel-based MRI and DTI study.

Journal of Alzheimer's disease : JAD - 1 Jan 2009

Honea Robyn A, Vidoni Eric, Harsha Amith, Burns Jeffrey M

Abstract excerpt

Neuroimaging studies of apolipoprotein E (ApoE4) have implicated its association with brain atrophy in Alzheimer's disease. To date, few studies have used automated morphological analysis techniques to assess ApoE4-related brain structure change in both gray and white matter in nondemented older adults. Nondemented (CDR = 0, n = 53) subjects over 60 had MRI, diffusion tensor imaging, and neurocognitive...

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Identifiers

PMID: 19584447
DOI: 10.3233/JAD-2009-1163
PMCID: PMC2892293

Genes

APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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