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Article

Effect of cyclooxygenase genotype and dietary fish oil on colonic eicosanoids in mice.

The Journal of nutritional biochemistry - 1 Aug 2012

Neilson Andrew P, Djuric Zora, Ren Jianwei, Hong Yu H, Sen Ananda, Lager Corey, Jiang Yan, Reuven Shony, Smith William L, Brenner Dean E

Abstract excerpt

Dietary ω3 fatty acids can modulate substrate availability for cyclooxygenases (COXs) and lipoxygenases, thus modulating downstream eicosanoid formation. This could be an alternative approach to using nonsteroidal anti-inflammatory drugs and other COX inhibitors for limiting Prostaglandin E(2) (PGE(2)) synthesis in colon cancer prevention. The aims of this study were to evaluate to what extent COX- and...

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Identifiers

PMID: 21937210
DOI: 10.1016/j.jnutbio.2011.05.003
PMCID: PMC3246564

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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