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Article

Highly purified eicosapentaenoic acid as free fatty acids strongly suppresses polyps in Apc(Min/+) mice.

Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Dec 2010

Fini Lucia, Piazzi Giulia, Ceccarelli Claudio, Daoud Yahya, Belluzzi Andrea, Munarini Alessandra, Graziani Giulia, Fogliano Vincenzo, Selgrad Michael, Garcia Melissa, Gasbarrini Antonio, Genta Robert M, Boland C Richard, Ricciardiello Luigi

Abstract excerpt

PURPOSE: Although cyclooxygenase (COX)-2 inhibitors could represent the most effective chemopreventive tool against colorectal cancer (CRC), their use in clinical practice is hampered by cardiovascular side effects. Consumption of ω-3-polyunsaturated fatty acids (ω-3-PUFAs) is associated with a reduced risk of CRC. Therefore, in this study, we assessed the efficacy of a novel 99% pure preparation of ω-3-PUFA...

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Source

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Identifiers

PMID: 21030497
DOI: 10.1158/1078-0432.CCR-10-1990
PMCID: PMC3795521

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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