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Article

The tail-module of yeast Mediator complex is required for telomere heterochromatin maintenance.

Nucleic acids research - 1 Jan 2012

Peng Jing, Zhou Jin-Qiu

Abstract excerpt

Eukaryotic chromosome ends have a DNA-protein complex structure termed telomere. Integrity of telomeres is essential for cell proliferation. Genome-wide screenings for telomere length maintenance genes identified several components of the transcriptional regulator, the Mediator complex. Our work provides evidence that Mediator is involved in telomere length regulation and telomere heterochromatin maintenance....

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Identifiers

PMID: 21930512
DOI: 10.1093/nar/gkr757
PMCID: PMC3258146

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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The tail-module of yeast Mediator complex is required for telomere heterochromatin maintenance.PMID 21930512Read ↗

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