Article
Genome-wide association of mediator and RNA polymerase II in wild-type and mediator mutant yeast.
Molecular and cellular biology - 1 Jan 2015
Paul Emily, Zhu Z Iris, Landsman David, Morse Randall H
Abstract excerpt
Mediator is a large, multisubunit complex that is required for essentially all mRNA transcription in eukaryotes. In spite of the importance of Mediator, the range of its targets and how it is recruited to these is not well understood. Previous work showed that in Saccharomyces cerevisiae, Mediator contributes to transcriptional activation by two distinct mechanisms, one depending on the tail module triad and...
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