Mediator complex dependent regulation of cardiac development and disease.

Abstract excerpt

Cardiovascular disease (CVD) is a leading cause of morbidity and mortality. The risk factors for CVD include environmental and genetic components. Human mutations in genes involved in most aspects of cardiovascular function have been identified, many of which are involved in transcriptional regulation. The Mediator complex serves as a pivotal transcriptional regulator that functions to integrate diverse cellular...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Cardiovascular Diseases
• Share to Cell Nucleus
• Share to Gene Expression Regulation