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Article

The Drosophila modigliani (moi) gene encodes a HOAP-interacting protein required for telomere protection.

Proceedings of the National Academy of Sciences of the United States of America - 17 Feb 2009

Raffa Grazia D, Siriaco Giorgia, Cugusi Simona, Ciapponi Laura, Cenci Giovanni, Wojcik Edward, Gatti Maurizio

Abstract excerpt

Several proteins have been identified that protect Drosophila telomeres from fusion events. They include UbcD1, HP1, HOAP, the components of the Mre11-Rad50-Nbs (MRN) complex, the ATM kinase, and the putative transcription factor Woc. Of these proteins, only HOAP has been shown to localize specif...

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PMID: 19181850
DOI: 10.1073/pnas.0812702106
PMCID: PMC2650146

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ATM

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19181850-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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The Drosophila modigliani (moi) gene encodes a HOAP-interacting protein required for telomere protection.PMID 19181850Read ↗

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The Drosophila Mre11/Rad50 complex is required to prevent both telomeric fusion and chromosome breakage.Semantic proximity Read ↗

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