Corticotropin-releasing hormone receptor type 1 (CRHR1) genetic variation and stress interact to influence reward learning.

doi:10.1523/JNEUROSCI.2661-11.2011

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Article

Corticotropin-releasing hormone receptor type 1 (CRHR1) genetic variation and stress interact to influence reward learning.

The Journal of neuroscience : the official journal of the Society for Neuroscience - 14 Sept 2011

Bogdan Ryan, Santesso Diane L, Fagerness Jesen, Perlis Roy H, Pizzagalli Diego A

Abstract excerpt

Stress is a general risk factor for psychopathology, but the mechanisms underlying this relationship remain largely unknown. Animal studies and limited human research suggest that stress can induce anhedonic behavior. Moreover, emerging data indicate that genetic variation within the corticotropin-releasing hormone type 1 receptor gene (CRHR1) at rs12938031 may promote psychopathology, particularly in the context...

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Identifiers

PMID: 21917807
DOI: 10.1523/JNEUROSCI.2661-11.2011
PMCID: PMC3185047

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CRHR1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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