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Article

Structural and mutational studies of a hyperthermophilic intein from DNA polymerase II of Pyrococcus abyssi.

The Journal of biological chemistry - 4 Nov 2011

Du Zhenming, Liu Jiajing, Albracht Clayton D, Hsu Alice, Chen Wen, Marieni Michelle D, Colelli Kathryn M, Williams Jennie E, Reitter Julie N, Mills Kenneth V, Wang Chunyu

Abstract excerpt

Protein splicing is a precise self-catalyzed process in which an intein excises itself from a precursor with the concomitant ligation of the flanking polypeptides (exteins). Protein splicing proceeds through a four-step reaction but the catalytic mechanism is not fully understood at the atomic level. We report the solution NMR structures of the hyperthermophilic Pyrococcus abyssi PolII intein, which has a...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 21914805
DOI: 10.1074/jbc.M111.290569
PMCID: PMC3207444

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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