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Article

Traceless protein splicing utilizing evolved split inteins.

Proceedings of the National Academy of Sciences of the United States of America - 7 Jul 2009

Lockless Steve W, Muir Tom W

Abstract excerpt

Split inteins are parasitic genetic elements frequently found inserted into reading frames of essential proteins. Their association and excision restore host protein function through a protein self-splicing reaction. They have gained an increasingly important role in the chemical modification of proteins to create cyclical, segmentally labeled, and fluorescently tagged proteins. Ideally, inteins would seamlessly...

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Identifiers

PMID: 19541616
DOI: 10.1073/pnas.0902964106
PMCID: PMC2708728

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Traceless protein splicing utilizing evolved split inteins.PMID 19541616Read ↗

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