Structural and dynamical features of inteins and implications on protein splicing.

Abstract excerpt

Protein splicing is a posttranslational modification where intervening proteins (inteins) cleave themselves from larger precursor proteins and ligate their flanking polypeptides (exteins) through a multistep chemical reaction. First thought to be an anomaly found in only a few organisms, protein splicing by inteins has since been observed in microorganisms from all domains of life. Despite this broad phylogenetic...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Amino Acids
• Share to Catalytic Domain
• Share to Models, Molecular