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Article

Stable albicidin resistance in Escherichia coli involves an altered outer-membrane nucleoside uptake system.

Journal of general microbiology - 1 Jan 1990

Birch R G, Pemberton J M, Basnayake W V

Abstract excerpt

Albicidin blocked DNA synthesis in intact cells of a PolA- EndA- Escherichia coli strain, and in permeabilized cells supplied with all necessary precursor nucleotides, indicating a direct effect on prokaryote DNA replication. Replication of phages T4 and T7 was also blocked by albicidin in albicidin-sensitive (Albs) but not in albicidin-resistant (Albr) E. coli host-cells. All stable spontaneous Albr mutants of...

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PMID: 2191080
DOI: 10.1099/00221287-136-1-51

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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