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Article

Stable albicidin resistance in Escherichia coli involves an altered outer-membrane nucleoside uptake system.

Journal of general microbiology - 1 Jan 1990

Birch R G, Pemberton J M, Basnayake W V

Abstract excerpt

Albicidin blocked DNA synthesis in intact cells of a PolA- EndA- Escherichia coli strain, and in permeabilized cells supplied with all necessary precursor nucleotides, indicating a direct effect on prokaryote DNA replication. Replication of phages T4 and T7 was also blocked by albicidin in albici...

Topics

Anti-Bacterial Agents
Cell Membrane
Chromosome Mapping
Dose-Response Relationship, Drug
Drug Resistance, Microbial
Escherichia coli
Mutation
Nucleosides
Organic Chemicals
Xanthomonas

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 2191080
DOI: 10.1099/00221287-136-1-51

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-2191080-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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