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Article

Inactivation of the RluD pseudouridine synthase has minimal effects on growth and ribosome function in wild-type Escherichia coli and Salmonella enterica.

Journal of bacteriology - 1 Jan 2011

O'Connor Michael, Gregory Steven T

Abstract excerpt

The Escherichia coli rluD gene encodes a pseudouridine synthase responsible for the pseudouridine (Ψ) modifications at positions 1911, 1915, and 1917 in helix 69 of 23S rRNA. It has been reported that deletion of rluD in K-12 strains of E. coli is associated with extremely slow growth, increased readthrough of stop codons, and defects in 50S ribosomal subunit assembly and 30S-50S subunit association. Suppressor...

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Identifiers

PMID: 21037010
DOI: 10.1128/JB.00970-10
PMCID: PMC3019933

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Source receipt: pubmed, retrieved 7 Sept 2026.

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