DNA looping in cellular repression of transcription of the galactose operon.

doi:10.1101/gad.4.3.410

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Article

DNA looping in cellular repression of transcription of the galactose operon.

Genes & development - 1 Mar 1990

Mandal N, Su W, Haber R, Adhya S, Echols H

Abstract excerpt

Communication between distant DNA sites is a central feature of many DNA transactions. Negative regulation of the galactose (gal) operon of Escherichia coli requires repressor binding to two operator sites located on opposite sides of the promoter. The proposed mechanism for regulation involves b...

Topics

DNA, Bacterial
Escherichia coli
Galactose
Gene Expression Regulation, Bacterial
Lac Operon
Microscopy, Electron
Mutation
Nucleic Acid Conformation
Operator Regions, Genetic
Operon
Repressor Proteins
Transcription Factors
Transcription, Genetic

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