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Article

Three-stage regulation of the amphibolic gal operon: from repressosome to GalR-free DNA.

Journal of molecular biology - 28 Apr 2006

Semsey Szabolcs, Virnik Konstantin, Adhya Sankar

Abstract excerpt

The gal operon of Escherichia coli is negatively regulated by the Gal repressosome, a higher order nucleoprotein complex containing a DNA loop that encompasses two gal promoters. In the repressosome structure, Gal repressor (GalR) dimers are bound to the two operator sites, flanking the promoter region, thus generating a DNA loop. The DNA loop is stabilized by binding of the architectural HU protein to the apex...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 16524589
DOI: 10.1016/j.jmb.2006.02.022

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Three-stage regulation of the amphibolic gal operon: from repressosome to GalR-free DNA.PMID 16524589Read ↗

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