Article
The transcriptional regulator GalR self-assembles to form highly regular tubular structures.
Scientific reports - 9 Jun 2016
Agerschou Emil D, Christiansen Gunna, Schafer Nicholas P, Madsen Daniel Jhaf, Brodersen Ditlev E, Semsey Szabolcs, Otzen Daniel E
Abstract excerpt
The Gal repressor regulates transport and metabolism of D-galactose in Escherichia coli and can mediate DNA loop formation by forming a bridge between adjacent or distant sites. GalR forms insoluble aggregates at lower salt concentrations in vitro, which can be solubilized at higher salt concentrations. Here, we investigate the assembly and disassembly of GalR aggregates. We find that a sharp transition from...
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