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Article

Specifically bound lambda repressor dimers promote adjacent non-specific binding.

PloS one - 1 Jan 2018

Sarkar-Banerjee Suparna, Goyal Sachin, Gao Ning, Mack John, Thompson Benito, Dunlap David, Chattopadhyay Krishnananda, Finzi Laura

Abstract excerpt

Genetic switches frequently include DNA loops secured by proteins. Recent studies of the lambda bacteriophage repressor (CI), showed that this arrangement in which the protein links two sets of three operators separated by approximately 2.3 kbp, optimizes both the stability and dynamics of DNA loops, compared to an arrangement with just two sets of two operators. Because adjacent dimers interact pairwise, we...

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Identifiers

PMID: 29608611
DOI: 10.1371/journal.pone.0194930
PMCID: PMC5880393

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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