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Article

DNA looping and unlooping by AraC protein.

Science (New York, N.Y.) - 26 Oct 1990

Lobell R B, Schleif R F

Abstract excerpt

Expression of the L-arabinose BAD operon in Escherichia coli is regulated by AraC protein which acts both positively in the presence of arabinose to induce transcription and negatively in the absence of arabinose to repress transcription. The repression of the araBAD promoter is mediated by DNA looping between AraC protein bound at two sites near the promoter separated by 210 base pairs, araI and araO2. In vivo...

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Source

Identifiers

PMID: 2237403
DOI: 10.1126/science.2237403

Genes

BAD

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

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Regulation of the l-arabinose operon of Escherichia coliSemantic proximity Read ↗

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Negative regulation of L-arabinose metabolism in Bacillus subtilis: characterization of the araR (araC) gene.Semantic proximity Read ↗

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