Article
Evidence of linkage to chromosomes 10p15.3-p15.1, 14q24.3-q31.1 and 9q33.3-q34.3 in non-syndromic colorectal cancer families.
European journal of human genetics : EJHG - 1 Jan 2012
Saunders Ian W, Ross Jason, Macrae Finlay, Young Graeme P, Blanco Ignacio, Brohede Jesper, Brown Glenn, Brookes Diana, Lockett Trevor, Molloy Peter L, Moreno Victor, Capella Gabriel, Hannan Garry N
Abstract excerpt
Up to 25% of colorectal cancer (CRC) may be caused by inherited genetic variants that have yet to be identified. Previous genome-wide linkage studies (GWLSs) have identified a new loci postulated to contain novel CRC risk genes amongst affected families carrying no identifiable mutations in any of the known susceptibility genes for familial CRC syndromes. To undertake a new GWLS, we recruited members from 54...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
