Susceptibility genetic variants associated with colorectal cancer risk correlate with cancer phenotype.

doi:10.1053/j.gastro.2010.05.072

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Article

Susceptibility genetic variants associated with colorectal cancer risk correlate with cancer phenotype.

Gastroenterology - 1 Sept 2010

Abulí Anna, Bessa Xavier, González Juan Ramón, Ruiz-Ponte Clara, Cáceres Alejandro, Muñoz Jenifer, Gonzalo Victoria, Balaguer Francesc, Fernández-Rozadilla Ceres, González Dolors, de Castro Luisa, Clofent Juan, Bujanda Luís, Cubiella Joaquín, Reñé Josep M A, Morillas Juan Diego, Lanas Angel, Rigau Joaquim, García Ana M A, Latorre Mercedes, Saló Joan, Fernández Bañares Fernando, Argüello Lídia, Peña Elena, Vilella Angels, Riestra Sabino, Carreño Ramiro, Paya Artemio, Alenda Cristina, Xicola Rosa M, Doyle Brian J, Jover Rodrigo, Llor Xavier, Carracedo Angel, Castells Antoni, Castellví-Bel Sergi, Andreu Montserrat

Abstract excerpt

BACKGROUND & AIMS: Ten common low-penetrant genetic variants have been consistently associated with colorectal cancer (CRC) risk; little is known about the correlation between these variants and CRC phenotype. Characterization of such a correlation would improve CRC management and prevention programs. We assessed the association between these genetic variants and CRC phenotype in patients and modeled pairwise...

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Identifiers

PMID: 20638935
DOI: 10.1053/j.gastro.2010.05.072

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