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Article

Enrichment of low penetrance susceptibility loci in a Dutch familial colorectal cancer cohort.

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Nov 2009

Middeldorp Anneke, Jagmohan-Changur Shantie, van Eijk Ronald, Tops Carli, Devilee Peter, Vasen Hans F A, Hes Frederik J, Houlston Richard, Tomlinson Ian, Houwing-Duistermaat Jeanine J, Wijnen Juul T, Morreau Hans, van Wezel Tom

Abstract excerpt

Recent genome-wide association studies have identified several loci that confer an increased risk of colorectal cancer (CRC). We studied the role of the 8q24.21 (rs6983267), 18q21.1 (rs12953717), 15q13.3 (rs4779584), 11q23.1 (rs3802842), 8q23.3 (rs16892766), and 10p14 () risk variants in a series of 995 Dutch CRC cases and 1340 controls. The CRC cases were selected on basis of having a family history of...

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PMID: 19843678
DOI: 10.1158/1055-9965.EPI-09-0601

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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