Analysis of mutations induced in the SUP4-o gene of Saccharomyces cerevisiae by cis-diammine dichloroplatinum(II).

doi:10.1093/carcin/11.4.633

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Article

Analysis of mutations induced in the SUP4-o gene of Saccharomyces cerevisiae by cis-diammine dichloroplatinum(II).

Carcinogenesis - 1 Apr 1990

Mis J R, Kunz B A

Abstract excerpt

A collection of 196 mutations induced in the SUP4-o gene of yeast by treatment with cis-diammine dichloroplatinum(II) (cis-DDP) was characterized by DNA sequencing. All possible types of base pair substitution were identified as well as deletions, insertions and double mutations. Base pair change...

Topics

Base Sequence
Cisplatin
DNA, Fungal
Genes, Fungal
Molecular Sequence Data
Mutation
Saccharomyces cerevisiae
Suppression, Genetic

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