Induction of tandem-base change mutations.

doi:10.1016/0027-5107(94)90037-x

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Article

Induction of tandem-base change mutations.

Mutation research - 1 Aug 1994

Hutchinson F

Abstract excerpt

Four databases with sequence changes for 12000 mutations in mammalian and bacterial cells were searched for genotoxic agents inducing tandem mutations, in which two adjacent base pairs are changed. Ultraviolet light induces about one CC > TT per 10-20 mutations, and other tandem-base changes at a...

Topics

Animals
Base Composition
Cisplatin
Databases, Factual
Mutagenesis
Mutagens
Mutation
Oxidants
Ultraviolet Rays

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