Article
Failure to detect an antimutator phenotype following disruption of the Saccharomyces cerevisiae DDR48 gene.
Current genetics - 1 May 1995
Roche H, Ramachandran K, Kunz B A
Abstract excerpt
The antimutator phenotype, reportedly conferred by disruption of the Saccharomyces cerevisiae DDR48 gene, was suggested to affect only a specific spontaneous mutational pathway. We attempted to identify the types of mutation that are DDR48-dependent by determining the specificity of the ddr48 antimutator. However, disruption of DDR48 did not decrease the rates of spontaneous forward mutation in a plasmid-borne...
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