Article
Impaired inhibitory control of cortical synchronization in fragile X syndrome.
Journal of neurophysiology - 1 Nov 2011
Paluszkiewicz Scott M, Olmos-Serrano Jose Luis, Corbin Joshua G, Huntsman Molly M
Abstract excerpt
Fragile X syndrome (FXS) is a neurodevelopmental disorder characterized by severe cognitive impairments, sensory hypersensitivity, and comorbidities with autism and epilepsy. Fmr1 knockout (KO) mouse models of FXS exhibit alterations in excitatory and inhibitory neurotransmission, but it is largely unknown how aberrant function of specific neuronal subtypes contributes to these deficits. In this study we show...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
