Article

Hypoplasticity in sensory-driven necortical circuits of Fragile X mice

2025-09-16

Abstract excerpt

Sensory experience and perceptual learning modify the receptive field properties of cortical pyramidal neurons (PNs), primarily through long-term potentiation (LTP). Repetitive sensory stimulation or rhythmic whisker stimulation (RWS), at behaviourally relevant frequencies (8 Hz), can induce long-term potentiation (LTP) of excitatory synapses in typically developing mice in the somatosensory cortex (S1). Fragile X...

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Literature Corpus work: 44a075ba-c9d2-5849-a72f-df19f54df637
DOI: 10.1101/2025.09.15.675519

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